固体脂质纳米粒的研究新进展New progress of study on solid lipid nanoparticles
丁立新,柴佳丽,李焕,杨珊珊,于莲,李守君,王佐卿
摘要(Abstract)：
目的:综述固体脂质纳米粒的研究新进展。方法:参阅国内外大量有代表性的论文,进行分析、归纳和总结。结果:比较了五种方法制备固体脂质纳米粒的优、缺点,其中以微乳化法和高压乳匀法(HPH)制备固体脂质纳米粒方法较好。介绍了固体脂质纳米粒的理化性质及其研究方法,讨论了适合于固体脂质纳米粒的不同给药途径。结论:固体脂质纳米粒作为一种新型的给药系统,虽存在一些问题有待解决,但却是一个很有发展前景的新型给药系统。
关键词(KeyWords)： 固体脂质纳米粒;制备方法;理化性质
基金项目(Foundation): 黑龙江省教育厅科学技术研究项目(12521559)
作者(Author): 丁立新,柴佳丽,李焕,杨珊珊,于莲,李守君,王佐卿
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